Regulatory Mechanisms of Strontium Mediated Oxidative Stress during Pregnancy and Its Impacts on Maternal and Infant Health

doi:10.12280/gjfckx.20250538

Abstract

Abstract:

Strontium is one of the essential trace elements in the human body. The strontium content in pregnancy women may have a certain impact on pregnancy outcomes, especially in terms of fetal growth and development and pregnancy-related complications. Research has shown that abnormal strontium content in pregnant women may participate in the pathological processes of pregnancy-related diseases by interfering with redox homeostasis. Oxidative stress is one of the pathogenic mechanisms of diseases such as pre-eclampsia, gestational diabetes mellitus, and fetal growth restriction. In recent years, studies have found that strontium can participate in the regulation of oxidative stress responses by regulating the activity of antioxidant enzymes and inhibiting lipid peroxidation, suggesting that it may play a certain role in maintaining oxidative balance during pregnancy. Therefore, maintaining an appropriate strontium level in pregnant women is potentially of great significance for reducing the risk of pregnancy complications such as pre-eclampsia and gestational diabetes mellitus, promoting normal fetal growth and development, and thus ensuring the health of both the mother and the infant.

Key words: Trace elements, Strontium, Oxidative stress, Pregnancy outcome, Pregnancy complications

DUAN Pu-chu, WANG Xiao-jian, ZHANG Yan-ling. Regulatory Mechanisms of Strontium Mediated Oxidative Stress during Pregnancy and Its Impacts on Maternal and Infant Health[J]. Journal of International Obstetrics and Gynecology, 2025, 52(5): 558-562.

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