Abstract: Objective： To compare the clinical characteristic and prognositic factors between uterine sarcoma and carcinosarcoma. Methods：By performing a retrospective analysis，we identified 168 women with pathology identified as uterine sarcoma or carcinosarcoma by Obstetrical and Gynecological Hospital of Fudan University from January 2003 to December 2012，and analysed their clinical information and follow up mortality and recurrence. Kaplan-Meier used to draw survival line and do single factor analysis，Log-rank test to compare two or more groups′ survival difference，multi-factor cox-regreesion model to screen the risk factors of prognosis. Results：Uterine sarcoma and carcinosarcoma′s median survival time were（125.76±4.99） months and （86.65±7.84） months respectively. Uterine sarcoma′s overall survival（OS） is significantly longer than carcinosarcoma（P=0.003），according to Cox multi-factors regression analysis，the risk factor for uterine sarcoma′s OS is tumor pathological stage（P=0.006），the risk factors for carcinosarcoma′s OS and progress-free survival （PFS） are not only stage（OS P=0.002，PFS P=0.007），but also lympha-node dissection（OS P=0.042，PFS P=0.042）. Conclusions： Compare to carcinosarcoma，uterine sarcoma have a better prognosis，it has a longer survival time for uterine sarcoma，the later tumor pathological stage，the shorter OS. For carcinosarcoma，not only the stage，lympha-node dissection can also improve their OS，and delay recurrence significantly.

Key words: Uterine neoplasms, Carcinosarcoma, Lymph node excision, Disease-free survival