Abstract: Multiple pregnancies and cervical incompetence are high risk factors for miscarriage or premature delivery. If multiple pregnancies complicated with cervical incompetence, the risk of miscarriage or premature delivery is higher. Two cases of multiple pregnancy complicated with cervical incompetence were reported. Multifetal pregnancy reduction was performed at 11+5 weeks of gestation and 20+5 weeks of gestation. Cervical cerclage was performed at 13+4 weeks of gestation and 21+6 weeks of gestation respectively. The cervical length was monitored by vaginal ultrasound and preterm delivery was prevented. The cases of multiple pregnancy complicated with cervical incompetence were born at 36 weeks of gestation and 33+4 weeks of gestation respectively. The clinical course was analyzed and evaluated. Cervical cerclage is a remedy to improve pregnancy outcome in multiple pregnancies. Cervical cerclage can repair the cervical function after multifetal pregnancy reduction. Periodic follow-up is very important to prevent premature delivery, so are clinical medication and removing cervical cerclage stitches in time to improve maternal and fetal prognosis. When multiple pregnancy complicated with cervical incompetence, multifetal pregnancy reduction combined with cervical cerclage is a choice for clinic practice.

Key words: Pregnancy reduction, multifetal, Cerclage, cervical, Uterine cervical incompetence, Prognosis