Abstract: Objective：To analyze the delivery outcomes and neonatal outcomes in the treatment of single-birth primipara oligohydramnios in labor using transvaginal amnioinfusion. Methods: 358 patients with single-birth primipara oligohydramnios in labor who were hospitalized in the Characteristic Medicine Center of the Chinese People′s Armed Forces from April 2015 to March 2018 were divided into two groups, including the treatment group (166 women those who accepted the transvaginal amnioinfusion) and the control group (192 women those who did not accept the transvaginal amnioinfusion). The delivery outcomes including spontaneous labor rate, forceps delivery rate, cesarean section rate, postpartum hemorrhage rate and puerperal infection rate, and the neonatal outcomes including umbilical artery PH, umbilical artery lactate, 1 minute Apgar score after birth, incidence of meconium aspiration syndrome (MAS) and admission rate of newborn department, were compared between the two groups. Results: The spontaneous labor ratein the treatment group was higher than that in the control group, while the forceps delivery rate and cesarean section rate were both lower than that in the control group. The difference of these three indexes between the treatment group and the control group were all statistically significant (P＜0.05). The difference of the postpartum hemorrhage rate and puerperal infection rate between the treatment group and the control group were both statistically insignificant (P＞0.05). The umbilical artery pH and 1 minute Apgar score after birth in the treatment group were both higher than that in the control group, while the umbilical artery lactate, incidence of MAS and admission rate of newborn department in the treatment group were all lower than that in the control group, and the difference of the these five indexes between the two groups were all statistically significant (P＜0.05). Conclusions: Transvaginal amnioinfusion is safe and effective in the treatment of single-birth primipara oligohydramnios in labor, which can improve obviously the delivery outcomes and neonatal outcomes.

Key words: Perfusion, Oligohydramnios, Natural childbirth, Cesarean section, Pregnancy outcome, Therapy