Abstract: Objective：To explore the feasibility, safety of laparoscopic treatment of hetertopic pregnancy (HP) and the effect on the outcome of pregnancy. Methods：34 HP patients with tubal pregnancy admitted to our hospital from January 2011 to January 2018 were selected for retrospective analysis, to explore the high-risk factors of hetertopic pregnancy, the feasibility of laparoscopic surgery and the pregnancy outcome. Results：There were 34 cases. Special cases included: 1 case of intrauterine twin pregnancy with right tubal pregnancy, 1 case of intrauterine pregnancy with right tubal interstitial pregnancy, and 1 case of intrauterine twin right uterine pregnancy with left tubal pregnancy. All the patients were treated with laparoscopic surgery and recovered well after surgery, operation time was 15-110 minutes, (45.21±8.33) min on average. Intraoperative hemorrhage was 5-200 mL, with an average was (33.04±10.12) mL. 3 cases with preoperative intraperitoneal hemorrhage more than 800 mL were treated with blood transfusion therapy in the operations. No fever, incision infection or complications were observed. Ultrasound suggest intrauterine pregnancy is normal after the operation for each patient and all patient recovered well. Only one case of artificial abortion was performed with missed abortion. All the rest has live births without birth defects. Conclusions：For patients with intrauterine pregnancy with unilateral tubal pregnancy during first trimester, laparoscopic surgery can safely remove ectopic pregnancy in the fallopian tube, and the operation is safe and effective, without increasing the incidence of iatrogenic abortion and birth defects.

Key words: Pregnancy, ectopic, Pregnancy, tubal, Laparoscopy, Pregnancy outcome, Reproduction techniques, assisted