Abstract: The incidence of ovarian neoplasms with high hematuria amylase is low, and it is easily misdiagnosed as malignant tumors with acute pancreatitis (AP). Clinically，AP should be excluded according to the population, imaging examination and typical etiology. The primary cause of amylase elevation should be considered by malignant tumor. This article reports a case of ovarian poorly differentiated serous adenocarcinoma with high blood urease amylase and misdiagnosed as AP, to analyze the pathogenesis and diagnostic considerations of high blood urease amylase, so as to deepen the understanding of the disease by clinicians and improve the level of diagnosis and treatment.

Key words: Ovarian neoplasms, Amylases, Hyperamylasemia, Pancreatitis