Journal of International Obstetrics and Gynecology ›› 2019, Vol. 46 ›› Issue (6): 632-635.

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Research Progress on the Associations of Vitamin D and Maternal Pregnancy Complications

LI Xiang,WU Xiao-ke   

  1. Clinical Medical School, Heilongjiang University of Chinese Medicne, Harbin 150040, China(LI Xiang);Department of Gynecology and Obstetrics,First Affiliated Hospital,Heilongjiang University of Chinese Medicine,Harbin 150040,China(WU Xiao-ke)
  • Received:2019-06-21 Revised:2019-07-19 Published:2019-12-15 Online:2019-12-15
  • Contact: WU Xiao-ke,E-mail:xiaokewu2002@vip.sina.com E-mail:18045141395@163.com
  • Supported by:
     

Abstract: As one of the essential nutrients, Vitamin D (VD) participates in regulating various biological processes in the human body. VD supplementation is mainly used to prevent and treat rickets, osteoporosis and so on. VD receptors are widely distributed in tissues and cells of the body widely. Studies have shown that VD plays an important role in modulating immune system functions. Meanwhile, it is involved in the pathogenesis of several disorders, such as nervous, endocrine and circulatory system diseases. Besides, VD is also crucial for maintaining maternal and fetal well-being during pregnancy. It has been reported that VD insufficiency or deficiency has been implicated in the increasing incidence of numerous maternal pregnancy complications. Moreover, severe VD deficiency is also associated with adverse maternal and fetal outcomes. In this article, we summarize the association between VD deficiency and maternal pregnancy complications and discuss the potential mechanism by consulting domestic and foreign literature published in recent years, aiming to provide theory basis for early screening, diagnosis and prompt treatment for VD deficiency.

Key words: Pregnant women, Vitamin D, Diabetes, gestational, Pre-eclampsia, Abortion, habitual, Depression, postpartum

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