Abstract:

Mammary-type myofibroblastoma (MTMF) is a rare benign mesenchymal-derived tumor that occurs outside of the breast and is composed of diffusely distribution of spindle cells, varying numbers of mature fat cells and coarse collagen fiber bundles. Immunophenotypically, the spindle cells in MTMF diffusely express CD34 and Desmin. Once diagnosed, regardless of its size or location, it should be surgically excised and regularly monitored postoperatively. This article reports a case of a 51-year-old postmenopausal woman with uterine MTMF, who was misdiagnosed as uterine leiomyoma preoperatively and intraoperatively. Based on the condition and patient′s wishes, total abdominal hysterectomy with bilateral salpingo-oophorectomy were performed, and MTMF was finally diagnosed by postoperative immunohistochemical staining and was followed up for 18 months with no specific discomfort. Through a retrospective analysis of the diagnosis and treatment process and experience of this case, this study aims to provide clinical reference for diagnosis and treatment.

Key words: Uterine neoplasms, Neoplasms, muscle tissue, Mammary glands, human, Pathology, Immunohistochemistry, Diagnosis, Therapy