Lesion Resection Combined with Skin Flap Transplantation in the Treatment of Recurrent Vulvar Paget′s Disease: A Case Report

doi:10.12280/gjfckx.20241114

Abstract

Abstract:

Vulvar Paget′s disease (VPD) is an extremely rare vulvar malignant tumor, mainly surgically treated. Although the mortality rate is low, the local recurrence rate is high. It is challenging to treat recurrent VPD. This article report the case data of a 74-year-old recurrent VPD. The patient visited the hospital due to vulva itching and oozing for 3 months after 7 years after VPD surgery. Gynecological examination revealed that the skin of the labia majora on both sides was hard, pigmentation and loss of pigmentation. A lesion can be seen in the upper part of the labia majora on the left vulva, 5 cm × 4 cm in size, hard, local red, surface rupture and scab, pathological biopsy showed that it meets VPD. Then the surgery of lesion resection combined with skin flap transplantation was performed. Imiquimod cream was treated with topical treatment. Now, nearly 5 years after the operation, the patient′s condition is stable and her quality of life is good. This case suggests that the efficacy of lesion resection combined with skin flap transplantation for multiple recurrent VPD is satisfactory.

Key words: Paget disease, extramammary, Recurrence, Surgical flaps, Skin transplantation, Reconstructive surgical procedures

CHEN Xiu-jie, WANG Ya-nan, CHENG Qian-qian, ZHANG Ji-wen, SONG Dian-rong. Lesion Resection Combined with Skin Flap Transplantation in the Treatment of Recurrent Vulvar Paget′s Disease: A Case Report[J]. Journal of International Obstetrics and Gynecology, 2025, 52(2): 237-240.

Figures/Tables 4

References 18

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