Abstract: Long non-coding RNA （lncRNA）, once regarded as "noise" in genomic transcription process, were ignored by the scientific community. However, more attentions are paid to lncRNA nowadays because recent studies have shown that they are not "junk" but functional RNAs. Although researches regarding to lncRNA are less because they are just "rising stars" in comparison to short non-coding RNA, these literatures have shown that lncRNA play important roles in the regulation of gene expression and provide immeasurable scientific value for future diagnosis and treatment of clinical disease especially for cancer. In this review, we summarized researches in the current status of the functions, mechanisms of lncRNA and their roles in the development of gynecological tumors.

Key words: RNA, Genital neoplasms, female, Long non-coding RNA