Journal of International Obstetrics and Gynecology ›› 2009, Vol. 36 ›› Issue (5): 343-347.

• 综述 • Previous Articles     Next Articles

Obese and Polycystic Ovary Syndrome in Adolescents

SUN Jing, WANG Yong, WU Xiao-ke   

  1. Key Laboratory of Medical Molecular Technology, Medical School, Nanjing University, Nanjing 210093, China(SUN Jing,WANG Yong); Department of Gynecology and Obstetrics, The First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China (WU Xiao-ke)
  • Received:2008-10-09 Revised:1900-01-01 Published:2009-10-15 Online:2009-10-15
  • Contact: WANG Yong

Abstract: Polycystic ovary syndrome (PCOS) is a common disorder among reproductive-aged women.
Recent research has elucidated that as the prevalence of pediatric obesity escalates, the morbidity of polycystic ovary syndrome in adolescent females is also increasing. Obesity contributes to the pathophysiology of polycystic ovary syndrome by increasing free insulin concentrations. Hyperandrogenism in PCOS can also increase visceral fat. Obesity can increase the morbidities of associated metabolic and cardiovascular dieases including insulin resistance (IR), dyslipidemia, hypertension and subclinical cardiovascular disease such as atherosclerosis. Early identification of adolescent polycystic ovary syndrome will help to correct and block the endocrine disorders, as well as the complications in the near future timely.

Key words: Polycystic ovary syndrome, Adolescent, Obesity, Hyperinsulinemia insulin resistance, Metabolic syndrome