Abstract: Tubal intraepithelial carcinoma is occult，which can be found in prophylactic salpingo-oophorectomies from women with BRCA mutations. Etilogy and the incidence of population is unknown. The incidence of women with BRCA mutations is 4.4%～8%. Positive peritoneal washings and pelvic implanted metastasis may appeared. The origin of the ovarian cancer has been debated. There are two ways of origin of ovarian cancer. High-grade serous carcinoma has been considered from fallopian. Tubal intraepithelial carcinoma has been diagnosed difficultly because of no early symptoms. Fallopian be required carefully checking after prophylactic salpingo-oophorectomies. Otherwise tubal intraepithelial carcinoma can be missed. Therapy is similar with ovarian cancer. We must attach importance to tubal intraepithelial carcinoma.

Key words: Fallopian tube neoplasms, Ovarian neoplasms, Genes, BRCA1, Genes, BRCA2