Abstract: Objective: To evaluate the clinical efficacy and safety of the improved anterior pelvic reconstruction combined with sacrospinous ligament suspension in treatment of anterior pelvic organ prolapse. Methods：55 cases with anterior pelvic organ prolapse （stage Ⅲ or stage Ⅳ according to POP-Q staging） from January 2010 to July 2012 were retrospectively analyzed. 17 cases received the improved anterior pelvic reconstruction and sacrospinous ligament suspension （the combination group），18 cases received only the improved anterior pelvic reconstruction （the reconstruction group），and 20 cases received the vaginal antetheca repair （the routine treatment group）. Results：There were significant differences in the average operation time，the amount of blood loss, and hospitalization day after operation in the three groups（P＜0.05）. There was no significant difference in the curative rate of one month after operation in the three groups，but the curative rate of 3 and 6 months after operation in the combination group was significantly higher than those in others groups （P＜0.05）. In the combination group and the reconstruction group, there were not adverse effects such as hematoma，urethra，bladder and rectum injury. However，there were 3 cases with the postoperative urinary retention in the routine treatment group. They recovered by heteropathy. Conclusions：The improved anterior pelvic reconstruction combined with sacrospinous ligament suspension can successfully repair defects of the anterior pelvic structure with better short-term efficacy, safe and feasible. However，its long-term efficacy needs further observation.

Key words: Gynecologic surgical procedures, Pelvic floor, Uterine prolapse, Improve anterior pelvic reconstruction, Sacrospinous ligament suspension, Repair of vaginal antetheca