Abstract: Objective: To evaluate the value of visual inspection with acetic acid（VIA）-visual inspection with Lugol’s iodine（VILI） in the early screening of cervical cancer. Methods: From May 2008-September 2008, 2 006 women having sexual life who are 30-59 years old were screened for the early lesions of cervical cancer in the community of Yingxin Street, in Dagang Disctrict, Tianjin. Cervical cells were collected and kept for LCT test. Then, apply 5% acetic acid and use the liquid coating method for VIA-VILI. The patients whose VIA-VILI were negative while the LCT were abnormal, and whose VIA or VILI were positive were done colposcopy examination and biopsy. Results: Finally, 2 000 people were brought into the test and 347 of them were diagnosed to be positive in VIA-VILI and were done biopsy, according to pathology, 47 people（13.54%） were equal or more than CIN Ⅱ. Meanwhile, 134 people were diagnosed to be positive in LCT and 50 people（37.31%） were equal or more than CIN Ⅱ based on pathology, and there were 39 people who were both been tested to be positive in VIA-VILI and LCT. The result of using VIA-VILI method to screen CIN Ⅱ and the sensitivity, specificity and some board index of cervical lesions and cervical cancer mentioned above were 81%, 84.6%, and 0.656 respectively. At the same time the result of using liquid based cytology method to screen them were 90.3%, 88.4%, and 0.787 respectively. Conclusions: Although the efficiency of using VIA-VILI test to screen cervical disease is lower than using liquid based cytology test, VIA-VILI test is cheap, convenient and fast, it is valuable for underdeveloped areas and lower-income people.

Key words: Uterine cervical neoplasms, Cervical intraepithelial neoplasia, Vaginal smears, Cytodiagnosis, Sensitivity and specificity