国际妇产科学杂志 ›› 2021, Vol. 48 ›› Issue (5): 575-578.doi: 10.12280/gjfckx.20210220

• 普通妇科疾病及相关研究:综述 • 上一篇    下一篇

胸腔子宫内膜异位综合征的诊治进展

潘钰文, 姚书忠()   

  1. 510080 中山大学附属第一医院妇产科
  • 收稿日期:2021-03-08 出版日期:2021-10-15 发布日期:2021-10-27
  • 通讯作者: 姚书忠 E-mail:yaoshuzh@sysu.edu.cn
  • 基金资助:
    国家自然科学基金面上项目(81874102);国家自然科学基金面上项目(82072874);广州市科技计划项目(202002020043);中山大学5010计划(2017006)

Advances in the Diagnosis and Treatment of Thoracic Endometriosis Syndrome

PAN Yu-wen, YAO Shu-zhong()   

  1. Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2021-03-08 Published:2021-10-15 Online:2021-10-27
  • Contact: YAO Shu-zhong E-mail:yaoshuzh@sysu.edu.cn

摘要:

子宫内膜异位症是育龄期女性常见的慢性疾病,其中胸腔子宫内膜异位综合征是较为罕见的一种类型。该病是子宫内膜组织异位到胸腔,从而引发多种与月经相关的胸腔受累的临床表现,包括气胸、血胸、咯血、肺结节和胸痛等,其中月经性气胸是最常见的。胸腔子宫内膜异位综合征的发病机制尚未完全明确,目前有多种假说解释子宫内膜组织是如何异位到胸腔以及月经性气胸的发病机制,但尚无一种假说可以单独解释胸腔子宫内膜异位综合征所有的临床表现。检查方法主要有影像学检查、组织学检查及其他检查等,其中影像学检查包括胸部X线、CT和磁共振成像(MRI)。治疗方式主要有药物治疗和手术治疗。药物治疗是一线治疗,其中,促性腺激素释放激素激动剂是一线用药。而对于药物治疗后仍复发或难以忍受药物治疗带来的不良反应的患者,应考虑手术治疗以根治疾病,并在术后辅以药物治疗。

关键词: 子宫内膜异位症, 胸腔子宫内膜异位综合征, 月经性气胸, 诊断, 治疗

Abstract:

Endometriosis is a common chronic disease in women of reproductive age, among which thoracic endometriosis syndrome is a relatively rare type. Endometrial-like tissue moves into the thoracic cavity and causes a variety of clinical manifestations related to the menstruation, including catamenial pneumothorax, hemothorax, hemoptysis, pulmonary nodules and chest pain. Among them, menstrual pneumothorax is the most common. The pathogenesis of this disease is not yet fully understood. At present, there are many hypotheses explaining how endometrial tissue moves into the thoracic cavity and the pathogenesis of menstrual pneumothorax, but there is no single hypothesis that can explain all the clinical manifestations of thoracic endometriosis syndrome. The examinations include radiological imaging (e.g., chest X-ray, CT and MRI), histological examination and so on. Management of this disease includes drug treatment and surgery. Drug therapy is the first-line treatment, among which gonadotropin-releasing hormone agonists are the first-line drugs. For patients who still relapse after drug treatment or cannot tolerate the adverse reactions caused by drug treatment, surgical treatment should be considered and drug treatment should be supplemented after surgery.

Key words: Endometriosis, Thoracic endometriosis syndrome, Catamenial pneumothorax, Diagnosis, Therapy