子宫腺肌病与不孕的相关性研究

doi:10.12280/gjfckx.20210233

摘要/Abstract

摘要：

子宫腺肌病（adenomyosis）好发于生育年龄女性,其引起的月经异常、痛经和不孕严重影响患者身体健康,尤其是子宫腺肌病引起的不孕症状严重影响患者的家庭生活,对于有保留生育要求的患者,其治疗是妇科和生殖科医生面临的一大难题。子宫腺肌病引起不孕的机制尚不清楚,其发生原因可能与宫腔形态改变、子宫结合带（uterine junctional zone）异常、子宫内膜改变、炎性介质和氧化应激,以及免疫功能失调等因素有关。综述子宫腺肌病与不孕的相关性研究。

关键词: 子宫腺肌病, 不育,女（雌）性, 生育力, 氧化性应激, 机制

Abstract:

Adenomyosis tends to occur in childbearing age women. The abnormal menstruation, dysmenorrhea and infertility caused by adenomyosis seriously affect the health of the patient. Especially, infertility seriously affect the family life of the patient. The treatment of patients with fertility preservation requirements is a major problem faced by gynecologists and reproductive doctors. Until now, the mechanism of infertility caused by adenomyosis is unclear. The cause may be related to the changes in uterine cavity morphology, abnormal uterine junctional zone, altered endometrial, inflammatory mediators and oxidative stress, immune dysfunction and other factors. This article reviews the research on the relationship between adenomyosis and infertility.

Key words: Adenomyosis, Infertility,female, Fertility, Oxidative stress, Mechanism

陈沫, 江秀秀. 子宫腺肌病与不孕的相关性研究[J]. 国际妇产科学杂志, 2021, 48(6): 646-650.

CHEN Mo, JIANG Xiu-xiu. Study on the Relationship between Adenomyosis and Infertility[J]. Journal of International Obstetrics and Gynecology, 2021, 48(6): 646-650.

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