国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (5): 355-358.

• 综述 • 上一篇    下一篇

子宫腺肌病的治疗现况

江小香, 项双卫   

  1. <SPAN lang=EN-US style=
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-10-15 发布日期:2010-10-15
  • 通讯作者: 江小香

Current Situation of the Treatments for Adenomyosis

JIANG Xiao-xiang，XIANG Shuang-wei   

  1. Department of Obstetrics and Gynecology of Fujian Medical University Union Hospital, Fuzhou 350001, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-10-15 Online:2010-10-15
  • Contact: JIANG Xiao-xiang

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摘要： 子宫腺肌病治疗方法有药物和手术治疗。临床常用药物有促性腺激素释放激素激动剂、口服避孕药、雄激素类衍生物、孕激素类和米非司酮，芳香化酶抑制剂和环氧化酶2抑制剂对子宫腺肌病的疗效正在探讨中，抗侵袭、抗血管生成药物、受体干预和基因治疗会逐步用于子宫腺肌病治疗。手术治疗包括根治手术和保守手术。根治手术即为子宫切除术，保守手术包括子宫内膜切除术、子宫腺肌瘤或子宫病灶切除术、盆腔去神经支配治疗术、腹腔镜下子宫动脉阻断术、子宫动脉栓塞术及磁共振引导下超声聚焦手术等。

关键词: 腺肌瘤, 子宫肿瘤, 药物疗法, 妇科外科手术

Abstract: Two treatments for adenomyosis are by pharmacology and surgery. The clinical commonly used medicines are gonadotropin-releasing hormone agonists, oral contraceptives, androgen derivatives, progesterone hormones, mifepristone; the efficacy of aromatase inhibitors and cycloo-xygenase-2 inhibitors for adenomyosis is being studied now; anti-invasion medicines, anti-angiogenesis medicines, receptor interference and gene therapy will be gradually used for the treatments for adenomyosis. Surgical treatments for adenomyosis includes radical surgery and conservative surgery. The radical surgery is hysterectomy. The conservative surgery includes endometrial resection, myometrial adenomyomas or uterine lesion resection, pelvic denervation surgery, laparoscopic uterine artery blockage, uterine artery embolization and magnetic resonance guided focused ultrasound surgery （MRgFUS） and so on.

Key words: Adenomyoma, Uterine neoplasms, Drug therapy, Gynecologic surgical procedures