国际妇产科学杂志

国际妇产科学杂志 ›› 2012, Vol. 39 ›› Issue (3): 276-280.

• 综述 • 上一篇    下一篇

重度妊娠期高血压疾病的降压治疗新进展

李 青, 林其德 , 狄 文   

  1. 200127 上海交通大学医学院附属仁济医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-06-15 发布日期:2012-06-15

New Advancement in the Treatments of Severe Hypertention in Pregnancies

LI Qing，LIN Qi-de，DI Wen   

  1. Department of Obstetrics and Gynecology，Renji Hospital Affiliated to Shanghai JiaoTong University School of Medicine，Shanghai 200127，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-06-15 Online:2012-06-15

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摘要： 妊娠期高血压疾病是一个世界关注的孕产妇健康问题，是导致发展中国家孕产妇死亡的主要原因之一。在妊娠期高血压疾病的各个时期都可能发生重度高血压。为了降低血管意外尤其是脑卒中和（或）其他中枢系统并发症的发生率，改善预后，应当积极、有效地治疗持续重度的高血压。而何时开始治疗、如何治疗仍然需要探讨。现有的文献资料显示，肼苯哒嗪和硝苯地平已不再是妊娠期高血压疾病降压治疗的一线药物，而拉贝洛尔、尼卡地平也许是更好的选择

关键词: 高血压, 妊娠性, 先兆子痫, 血压, 拉贝洛尔, 尼卡地平

Abstract: Hypertensive disorders of pregnancies remains a central public health concern throughout the world，and is a major cause of maternal mortality in the developing country. Acute severe hypertension may occur in different period of the hypertensive disorders of pregnancy. In order to decrease the incidence of adverse vascular events，persistent severe hypertension must be treated effectively， particularly stroke or other central nervous system complications. However，when and which antihypertensive agents to use remain considerable.As far as what we are concerned，hydralazine and nifedipine are no longer the first choice，but labetalol and nicardipine may be a good choice.

Key words: Hypertension, pregnancy-induced, Pre-eclampsia, Blood pressure, Labetalol, Nicardipine