国际妇产科学杂志

国际妇产科学杂志 ›› 2014, Vol. 41 ›› Issue (4): 453-458.

• 论著 • 上一篇    下一篇

单纯针灸相关疗法治疗原发性痛经效果的系统评价

秦爱玲，马瑞萍，肖婉，易莉娟，田旭   

  1. 730000 兰州，甘肃省第二人民医院妇产科（秦爱玲，马瑞萍，肖婉）；天津中医药大学研究生院（易莉娟，田旭）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-08-15 发布日期:2014-08-15
  • 通讯作者: 田旭

Effects of Associated Simple Acupuncture Therapy in the Treatment of Primary Dysmenorrhea：a Systematic Review

QIN Ai-ling，MA Rui-ping，XIAO Wan，YI Li-juan，TIAN Xu   

  1. Department of Obstetrics and Gynecology，The Second People′s Hospital of Gansu Province，Lanzhou 730000，China（QIN Ai-ling，MA Rui-ping，XIAO Wan）；Graduate College of Tianjin University of TCM，Tianjin 300193，China（YI Li-juan，TIAN Xu）
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-08-15 Online:2014-08-15
  • Contact: TIAN Xu

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摘要： 目的：系统评价单纯针灸相关疗法治疗原发性痛经（primary dysmenorrhea，PD）的效果。方法：计算机检索PubMed、Web of Science（SCI）、中国生物医学文献数据库（CBM）、中国期刊全文数据库（CNKI）、中文期刊全文数据库（VIP）及万方数字化期刊全文数据库（WANFANG DATA）等数据库中关于单纯针灸相关疗法治疗PD的随机对照试验（RCTs），检索时限均为从建库至2012年12月。依据纳入与排除标准独立检索上述数据库、筛选文献、提取资料及文献质量评价后，利用Cochrane协作网提供的RevMan 5.2.4 软件进行Meta 分析。结果：最终纳入20个RCTs，共2 134例患者。Meta分析结果显示：①单纯针灸相关疗法治疗组患者的总疗效优于对照疗法组，差异有统计学意义（RR=1.19，95%CI：1.14～1.24，P＜0.000）和（RR=1.15，95%CI：1.10～1.21，P=0.03）。②在痛经症状方面，单纯针灸相关疗法治疗组患者症状缓解程度明显优于对照疗法组，差异有统计学意义（MD=3.20，95%CI：2.36～3.04，P＜0.000）和（MD=2.09， 95%CI：0.16～4.02，P=0.03）。③对于降低外周血前列腺素F2α（prostaglandins F2α，PGF2α），两组差异无统计学意义（MD=0.13，95%CI：-0.13～0.39，P=0.32）。结论：单纯针灸相关疗法能有效地缓解PD患者的症状，且在总有效率方面也具有显著的优势。因本次纳入研究的数量和质量存在一定局限，上述结论尚待开展大样本、多中心研究加以验证。

关键词: 中医疗法, 痛经, Meta分析, 随机对照试验

Abstract: Objective： To systematically review the effectiveness of associated simple acupuncture therapy in the treatment of primary dysmenorrhea（PD）. Methods：Databases such as PubMed，Web of Science（SCI），CBM，CNKI，VIP and WANFANG DATA were electronically searched to collect the randomized controlled trials（RCTs）（up to December 2012），and the relevant references of the included articles were also manually searched. According to the inclusion and exclusion criteria，literature was screened，data were extracted and methodological quality of the included studies was assessed. Then Meta analyses were performed by using RevMan 5.2 software. Results：A total of 20 RCTs involving 2 134 participants were included. Results of Meta analyses showed that：①total efficiency of associated simple acupuncture therapy was better than that of control method，with statistically significant differences [RR=1.19，95%CI（1.14，1.24），P＜0.000] and [RR=1.15，95%CI（1.10，1.21），P=0.03]. ②Associated simple acupuncture therapy was better than control method in releasing degree of serious symptoms of PD，with statistically significant differences [MD=3.20，95%CI（2.36，3.04），P＜0.000] and [MD=2.09，95%CI（0.16，4.02），P=0.03]. ③ There was no statistical difference in reducing level of the peripheral blood prostaglandin F2α between the two groups [MD=0.13，95%CI（-0.13，0.39），P=0.32]. Conclusions：Associated simple acupuncture therapy can significantly relieve pain in patients with PD and overall efficiency. Due to limitations on the quantity and quality of included studies，this conclusion has yet to be carried out in large， multicenter study to verify.

Key words: TCM therapy, Dysmenorrhea, Meta-analysis, Randomized controlled trail