关键词: 妊娠, 卵巢肿瘤, 颗粒细胞瘤, 幼年型颗粒细胞瘤

Abstract: Objective：To analyze clinical features，diagnosed key points, treatment and prognosis of juvenile granulose cell tumor (JGCT) during pregnancy in order to improve the level of differential diagnosis. Methods：To analyze retrospectively clinical data of 1 patient with JGCT occurred of pregnancy and review relevant literatures. Results：A 27-year-old female patient was admitted for menolipsis after 39+3 weeks, intermittent right lower abdomen pain 3 days. Ultrasonography suggested that there was a mixed echogenic mass in the right lower abdominal containing solid and cystic components. The cancer antigen-125 (CA125) was 32.3 U/mL, CA19-9 was 19.1 U/mL. Preoperative diagnosis was threatened labor and pelvic mass (uncertain quality). Cesarean delivery and exploratory laparotomy were carried out. A cystic mass ruptured was founded in the right ovary. Resection of the right ovarian mass was performed. And the postoperative pathological diagnosis was ovarian JGCT. The second laparotomy was given: resection of the right ovary and fallopian tube，a wedge biopsy of the left ovary，pelvic lymph node biopsy, part of the large net excision and appendectomy. The patient received postoperative chemotherapy with cisplatinum, vincristine and Blenmyc (PVB) for 3 courses. And the tumor had no recurrence for eight monthes. Conclusions：JGCT is rare, especially in pregnancy. Diagnosis can be confirmed by pathological examination and immunohistochemical staining.

Key words: Pregnancy, Ovarian neoplasms, Granular cell tumor, Juvenile granulose cell tumor