国际妇产科学杂志 ›› 2020, Vol. 47 ›› Issue (6): 605-610.

• 综述 •    下一篇

妊娠期妇科恶性肿瘤的治疗进展

田蕾,辛玉琦,黄梦微,王晓慧   

  1. 730000  兰州大学第一临床医学院,兰州大学第一医院妇产科,甘肃省妇科肿瘤重点实验室
  • 收稿日期:2020-05-21 修回日期:2020-07-28 出版日期:2020-12-15 发布日期:2020-12-11
  • 通讯作者: 王晓慧,E-mail:xiaohuiwang2015@163.com E-mail:xiaohuiwang2015@163.com

Advances in the Treatment of Gynecological Malignancies during Pregnancy

TIAN Lei, XIN Yu-qi, HUANG Meng-wei, WANG Xiao-hui   

  1. The First Clinical Medical College of Lanzhou University, Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Gansu Province Key Laboratory of Gynecological Oncology, Lanzhou 730000 , China
  • Received:2020-05-21 Revised:2020-07-28 Published:2020-12-15 Online:2020-12-11
  • Contact: WANG Xiao-hui, E-mail:xiaohuiwang2015@163.com E-mail:xiaohuiwang2015@163.com

摘要: 宫颈癌、子宫内膜癌和卵巢癌是妇科常见的三大恶性肿瘤,目前发病年龄逐渐趋于年轻化。妊娠期妇科恶性肿瘤虽不常见,但近年已有流行病学研究证实其发病率不断上升,宫颈癌和卵巢癌是妊娠期被诊断出的最常见的妇科肿瘤,妊娠期子宫内膜癌罕见。由于妊娠期妇科恶性肿瘤临床管理的复杂性,其治疗方法也愈发受到重视,需综合考虑肿瘤分期、分化程度、组织学类型、孕周、患者的意愿及可能的胎儿结局,多学科全面地评估病情,制定个体化治疗方案,择机行保守治疗、手术治疗或化疗,在保障母体健康的基础上最大程度地降低恶性肿瘤对胎儿的影响,维持妊娠和母体生育功能。本文综述妊娠期妇科恶性肿瘤不同治疗方法以取得更佳母婴结局,以期为临床提供借鉴经验。

关键词: 宫颈肿瘤;, 卵巢肿瘤;, 子宫内膜肿瘤;, 妊娠;, 妊娠结局;, 治疗

Abstract:  Cervical cancer, endometrial cancer and ovarian cancer are three common malignant tumors in gynecology. At present, the age of onset tends to be younger. Although gynecological malignancies are not common in pregnancy, epidemiological studies have been confirmed that the incidence rate of these diseases has been increasing in recent years. Cervical and ovarian cancers are the most common gynecological cancers in pregnancy, and endometrial cancer is rare in pregnancy. Due to the complexity of clinical management of gynecological malignancies during pregnancy, its treatment methods have been paid more attention. It is necessary to comprehensively consider the tumor stage, differentiation degree, histological type, gestational week, wishes of patients and possible fetal outcomes, comprehensively evaluate the condition of the disease and formulate individualized treatment plan. Conservative treatment, surgical treatment or chemotherapy can reduce the influence of malignant tumor on fetus and maintain pregnancy and maternal reproductive function on the basis of maternal health. In this paper, different treatment methods of gynecological malignant tumor in pregnancy were summarized in order to achieve better maternal and infant outcomes and provide reference for clinical experience.

Key words: Uterine cervical neoplasms; , Ovarian neoplasms;, Endometrial neoplasms;, Pregnancy;, Pregnancy outcomes;, Therapy