卵巢中肾样腺癌伴交界性肿瘤一例并文献复习

doi:10.12280/gjfckx.20210428

摘要/Abstract

摘要：

卵巢中肾样腺癌（mesonephric-like adenocarcinoma）是一种表现为中肾分化的腺癌,其来源尚不确定,国内外相关报道极少。该病的诊断与治疗无特定规范,报道1例67岁女性双侧卵巢囊实性肿物,高度怀疑卵巢恶性肿瘤,给予手术治疗,术后病理诊断为双侧卵巢中肾样腺癌伴交界性浆黏液性肿瘤,该病临床表现无特异性,其病理免疫组织化学以雌激素受体（estrogen receptor,ER）和孕激素受体（progesterone receptor,PR）阴性、GATA3和甲状腺转录因子1（thyroid transcription factor-1,TTF-1）表达为特征,因缺乏该病术后特定诊疗规范,术后拟给予紫杉醇加卡铂化疗6个疗程,通过分析该病例,旨在为该病后续研究提供更多诊治参考。

关键词: 中肾瘤, 卵巢肿瘤, 腺癌,黏液, 诊断, 治疗, 预后, 病例报告, 中肾样腺癌

Abstract:

Mesonephric-like adenocarcinoma of the ovary is a kind of adenocarcinoma presenting as mesonephric-like differentiation. The origin of mesonephric-like adenocarcinoma is uncertain, and the related reports at home and abroad are few. There are no relevant guidelines for diagnosis and treatment of this disease. A 67-year-old woman with bilateral solid ovarian cyst and highly suspected malignant ovarian tumor was treated by operation, the postoperative pathological diagnosis was bilateral ovarian mesonephric-like adenocarcinoma with borderline serous mucinous tumor. The clinical manifestations of the disease were nonspecific. Its pathological immunohistochemistry was characterized by negative ER and PR, GATA3 and TTF-1 expression. Due to the lack of specific postoperative diagnosis and therapeutic criteria for this disease, the postoperative chemotherapy regimen of paclitaxel plus carboplatin for 6 courses was proposed. The analysis of this case was intended to provide more reference for diagnosis and treatment of this disease for subsequent studies.

Key words: Mesonephroma, Ovarian neoplasms, Adenocarcinoma,mucinous, Diagnosis, Therapy, Prognosis, Case reports, Mesonephric-like adenocarcinoma

张世凯, 刘晓慧, 朱可欣, 左香灵, 田庚. 卵巢中肾样腺癌伴交界性肿瘤一例并文献复习[J]. 国际妇产科学杂志, 2022, 49(1): 53-55.

ZHANG Shi-kai, LIU Xiao-hui, ZHU Ke-xin, ZUO Xiang-ling, TIAN Geng. Mesonephric-Like Adenocarcinoma with Borderline Tumor in Ovary: A Case Report and Literature Review[J]. Journal of International Obstetrics and Gynecology, 2022, 49(1): 53-55.

图/表 1

参考文献 11

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