生殖道菌群在妊娠中的作用

doi:10.12280/gjfckx.20230168

摘要/Abstract

摘要：

生殖道菌群种类繁多，相互共生拮抗，在防御感染、促进妊娠、维持正常宫内环境等方面发挥重要作用。生殖道菌群与宿主相互作用产生的代谢产物不仅与菌群失调、宿主免疫有关，也与不良妊娠结局具有相关性。近年来，生殖道菌群在妊娠中作用的相关性研究逐渐受到学界的关注，故从阴道及宫颈菌群、宫腔菌群、输卵管及卵泡液菌群在正常妊娠中的作用，以及生殖道常见微生物与不良妊娠结局的相关性等方面试图阐述生殖道菌群与宿主之间复杂的相互作用，以期为研究不良妊娠结局发生的作用机制及治疗提供依据。

关键词: 微生物群, 生殖道感染, 生殖器, 女（雌）性, 妊娠结局, 菌群失调

Abstract:

There are many kinds of reproductive tract flora, which are symbiotic and antagonistic to each other. They play an important role in defending infection, promoting pregnancy and maintaining a normal intrauterine environment. The metabolites produced by the interaction between the reproductive tract flora and the host are not only related to flora imbalance and host immunity, but also related to adverse pregnancy outcomes. In recent years, the research on the correlation between the role of reproductive tract flora in pregnancy has gradually attracted the attention of the academic community. Therefore, this article attempts to explain the complex interaction between the reproductive tract flora and the host from the aspects of the role of vaginal and cervical flora, uterine cavity flora, fallopian tube and follicular fluid flora in normal pregnancy, as well as the correlation between common microorganisms in the reproductive tract and adverse pregnancy outcomes, in order to provide a basis for studying the mechanism and treatment of adverse pregnancy outcomes.

Key words: Microbiota, Reproductive tract infections, Genitalia, female, Pregnancy outcomes, Dysbacteriosis

穆新丹, 郭洁. 生殖道菌群在妊娠中的作用[J]. 国际妇产科学杂志, 2023, 50(4): 416-420.

MU Xin-dan, GUO Jie. The Role of Reproductive Tract Flora in Pregnancy[J]. Journal of International Obstetrics and Gynecology, 2023, 50(4): 416-420.

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