国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (5): 311-313.

• 综述 • 上一篇    下一篇

人乳头瘤病毒与子宫颈癌临床关系研究进展

张艾芃, 李亚里   

  1. 100583 北京,中国人民解放军总医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-10-15 发布日期:2010-10-15

Progress in Clinical Relationship Between Human Papillomavirus and Cervical Cancer

ZHANG Ai-peng, LI Ya-li   

  1. Department of Obstertrics and Gynecology, General Hospital of PLA, Beijing 100853, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-10-15 Online:2010-10-15

摘要: 人乳头瘤病毒(HPV)在女性人群中感染率较高,与子宫颈癌及癌前病变关系密切。目前公认HPV是引起上述病变的主要致病因素。子宫颈癌是一种常见妇科恶性肿瘤,其发病率逐年上升,全世界每年约有四十七万新发病例,并导致23万人死亡。随着分子生物学与流行病学的发展,对HPV的检测和治疗成为预防子宫颈癌的重要手段。HPV疫苗研究及临床应用也进入崭新的时代。对HPV与子宫颈癌相关性的研究进展综述。

关键词: 乳头状瘤病毒科, 宫颈肿瘤, 宫颈上皮内瘤样病变, 乳头状瘤病毒疫苗

Abstract: The human papillomavirus (HPV) is the most commonly infection among women. Infection with
certain types of HPV is recognised as a main reason for cervical precancerous lesion and invasive cervical cancer worldwide. Cervical cancer is the second most common malignant tumors in gynecology. Every year about 47 million new cases, and cause 23 million deaths around the world, with the development of molecular biology and epidemiology, HPV DNA testing and treatment become an important method of preventing cervical cancer. HPV vaccine research has entered a new era. With the more research about the relationship between HPV and cervical cancer, for making further research, this paper reviews the new progress of HPV and cervical cancer.

Key words: Papillomaviridae, Uterine cervical neoplasms, Cervical intraepithelial neoplasia, Papillomavirus vaccines