Journal of International Obstetrics and Gynecology ›› 2021, Vol. 48 ›› Issue (5): 543-547.doi: 10.12280/gjfckx.20210021

• Research on Gynecological Malignancies: Review • Previous Articles     Next Articles

Research Progress on the Relationship between Uterine Fibroids and Vitamin D

WANG Zi-hao, ZHOU Jian-zheng(), WANG Mei-yun, YANG Ling   

  1. Shanxi Medical University, Taiyuan 030000, China (WANG Zi-hao, WANG Mei-yun); Department of Obstetrics and Gynecology, The Second Hospital of Shanxi Medical University, Taiyuan 030000, China (ZHOU Jian-zheng, YANG Ling)
  • Received:2021-01-08 Published:2021-10-15 Online:2021-10-27
  • Contact: ZHOU Jian-zheng E-mail:932882672@qq.com

Abstract:

Uterine fibroids are common benign tumors in gynecology, which seriously affect women′s quality of life. The current idea of clinical treatment of uterine fibroids is to formulate different conservative treatment plans or surgical treatment plans based on individual differences, but these treatment plans have drawbacks. For many years, the medical profession has been looking for better treatments for uterine fibroids, and the relationship between vitamin D and uterine fibroids has also been discovered. As a steroid compound, vitamin D plays an important role in various organs and tissues of the human body. The confirmed obstetrics and gynecology diseases related to vitamin D include infertility, polycystic ovary syndrome and premature delivery. Studies in the past decade have confirmed that reduced levels of vitamin D in the human body are one of the risk factors for the occurrence and development of uterine fibroids. Some current studies have also found that drug supplementation with vitamin D and its analogues can play a role in the treatment of uterine fibroids.

Key words: Vitamin D, Uterus, Myoma, Receptors,calcitriol, Drug therapy