Abstract:

The incidence of colorectal cancer in pregnancy is low and rare in clinical practice. There is no consensus on the diagnosis method, timing of pregnancy termination and treatment options for colorectal cancer in pregnancy. This article reports a case of colon cancer in pregnancy with ovarian and abdominal metastases, who presented to the clinic with abdominal distension in mid-pregnancy, and a large amount of ascites were seen in ultrasound examination. Combining MRI, tumor index and multi-disciplinary team suggestions, it was considered that possibility of malignancy was high and recommended that abdominal puncture be performed to examine ascites for a clear diagnosis. Based on the pathological findings of ascites, a diagnosis of pregnancy with malignant tumors (poorly differentiated adenocarcinoma of the digestive tract) was made. After seeking the consent of the patient and her family members, she was induced with Levanon amniotic cavity injection midterm. Postpartum enteroscopy revealed poorly differentiated adenocarcinoma of the sigmoid colon and chemotherapy for the primary disease was administered one month after delivery. Meanwhile, the relevant literature was reviewed to provide experience for the diagnosis and treatment of colorectal cancer in pregnancy.

Key words: Pregnancy trimester, second, Colonic neoplasms, Neoplasm metastasis, Termination of pregnancy, Multi-disciplinary team