Application Progress of Bioengineering Principle in Cervical Remodeling and Spontaneous Preterm Labor

doi:10.12280/gjfckx.20240256

Abstract

Abstract:

The mechanical function of the cervix is critical for the normal progression of pregnancy. During normal pregnancy, the cervix softens significantly and becomes more compliant, which are essential for maintaining pregnancy and facilitating a successful delivery. Abnormal cervical remodeling is believed to contribute to spontaneous preterm labor. Currently, there are limited methods available for predicting spontaneous preterm labor, with transvaginal ultrasound being the most commonly applied in clinical approach to measure cervical canal length. With the development of bioengineering, it is possible for related technologues to be applied in scientific research and further practice in clinical work. This article mainly summarized the application of bioengineering principles and technologies such as electrical impedance spectroscopy, ultrasound shear wave elastography, diffusion tensor imaging, cervical aspiration, and Raman spectroscopy in predicting spontaneous preterm labor and establishing models of cervical remodeling, as well as the exploration of new materials such as biocompatible hydrogels in preventing spontaneous preterm labor.

Key words: Principle of bioengineering, Cervix Uteri, Cervical remodeling, Spontaneous preterm labor, Biomechanical model

CHEN Xin-xin, LI Mao, JIANG Feng. Application Progress of Bioengineering Principle in Cervical Remodeling and Spontaneous Preterm Labor[J]. Journal of International Obstetrics and Gynecology, 2024, 51(4): 453-457.

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