Abstract: Objective：To explore whether anti-mullerian hormone（AMH） measurement in the serum could be a marker for diagnosis of polycystic ovary syndrome（PCOS）. Methods：Serum AMH was measured with immunoassay in a cohort of 75 PCOS patients and 86 controls，and follicle number was estimated by ultrasound scanning. Results：Serum AMH levels were 4-fold higher in PCOS patients than in control group［（8.21±2.32） mg/L vs.（2.39±1.29） mg/L］，and were significantly related to the follicle number in the two groups. In PCOS patients，AMH concentrations correlated with the number of ovarian follicles、testosterone、LH and LH/FSH（r= 0.489，0.215，0.312 and 0.256，P＜0.05），but not related with FSH、E2 PRL and BMI（r=0.12，0.19，0.10 and 0.16，P＞0.05）.Conclusions：The serum AMH level was a marker which may be used for diagnosis of the PCOS.

Key words: Anti-mullerian hormone, Polycystic ovary syndrome, Follicle stimulating hormone, Estradiol, Testosterone