Abstract: Objective：To evaluate the association of ovarian transposition procedures in preserving ovarian function in relation to the location of the transposed ovaries in young cercical carcinoma patients who underwent the radiotherapy. Methods：The clinical data of 72 young patients with cervical cancer who underwent ovarian transposition between June 2012 and June 2016 in Wuzhou Red Cross Hospital were analyzed retrospectively. Ovarian endocrine function was assessed by observing the symptoms of perimenopausal period and serum FSH, LH, E2 level. Results：Based on receiver operator characteristic curve analysis, optimum cutoff value of location more than 1.5 cm above the iliac crest was significantly associated with preservation of ovarian function after treatment (area under receiver operator characteristic curve: 0.747, 95%CI: 0.593-0.902). Optimum cutoff value of age was 32.5 (area under receiver operator characteristic curve: 0.692, 95%CI: 0.522-0.860). Multivariate analysis confirmed that the location of transposed ovary higher than or equal to 1.5 cm above the iliac crest (OR=0.09, 95%CI：0.014-0.571) and less than or equal to 32.5 years old (OR=0.062, 95%CI: 0.006~0.655) were the most important factor for preserve ovarian function. Conclusions：The position of transposed ovary higher than 1.5 cm above the iliac crest is recommended to avoid ovarian damage after ovarian transposition after radiotherapy in young cervical carcinoma women.

Key words: Uterine cervical neoplasms, Radiotherapy, Age factors, Ovarian transposition