Abstract: Objective：To investigate the clinical features of pregnancy complicated with acute leukemia, in order to improve the diagnosis and treatment level of the disease. Methods：To analyze retrospectively the diagnosis and treatment process of 1 case with acute myeloid leukemia, and refer to related literature. Results：In this case, acute myeloid leukemia was found in the late pregnancy. After correcting anemia, promoting fetal lung maturity, protecting brain nerve cells and other symptomatic treatment, the patient bore a live baby girl in caesarean section at 32+1 week of gestation. Then she recevied a series of standard chemotherapy. The literatures show that patients diagnosed with acute leukaemia during the first trimester are recommended to terminate pregnancy. Exposure to chemotherapeutic drugs in the second and third days of pregnancy will increase the risk of intrauterine growth restriction and premature birth, but it does not increase the risk of fetal malformation. A treatment plan can be made according to the gestational week. Conclusions：The treatment of pregnancy combined with leukemia should take account of various factors such as disease itself, mother, fetus and patient's wishes. It is necessary for multidisciplinary team cooperation to choose the best treatment plan to reduce the incidence of adverse pregnancy outcomes.

Key words: Leukemia, myeloid, acute, Pregnancy complications, hematologic, Therapy, Case reports