Abstract: Endometriosis（EMs） is a common gynecological disease, which often occurs in women of reproductive age. Pelvic pain and infertility are the main manifestations, which seriously disturb the physical and mental health of reproductive women. Recent studies have found that EMs can not only cause infertility, but also lead to adverse pregnancy outcomes. Studies have shown that women with EMs had a statistically significantly higher risk of miscarriage, ectopic pregnancy in the early pregnancy outcomes, and preterm birth, placenta previa, gestational hypertension and preeclampsia, small for gestational age, and cesarean delivery in the middle-late pregnancy outcomes compared with the healthy controls. EMs is associated with these above adverse pregnancy outcomes. The mechanism of EMs leading to infertility and adverse pregnancy outcomes is complex. It involves the pathophysiological changes of EMs during its occurrence and development. It is important to elucidate the mechanism of EMs for the prevention and treatment of adverse pregnancy outcomes in EMs patients.

Key words: Endometriosis, Pregnancy outcome, Abortion, spontaneous, Premature birth, Placenta previa