Journal of International Obstetrics and Gynecology ›› 2020, Vol. 47 ›› Issue (2): 212-216.

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Research Progress on Diagnosis, Treatment and the Relation between Endometrial Cancer and Adenomyosis

YANG Hui-juan,YU Ting,HAN Xu   

  1. Department of Obstetrics and Gynecology,The First Affiliated Hospital of Harbin Medical University,Harbin 150000,China
  • Received:2019-10-14 Revised:2019-12-01 Published:2020-04-15 Online:2020-04-15
  • Contact: HAN Xu,E-mail:hanxu_hyd@163.com E-mail:hanxu_hyd@163.com
  • Supported by:
     

Abstract: Adenomyosis is characterized by the presence of endometrial glands and stroma in myometrium. It is a common disease that cause significant symptoms such as hypermenorrhea and progressive dysmenorrhea in reproductive-aged women, and seriously affect patients′ quality of life. The pathogenesis of the disease is not clear. There are many theories such as endometrial injury depression theory, epithelial mesenchymal transformation theory, stem cell theory and so on. Histological examination is the gold standard of diagnosis. The clinical manifestations and imaging findings of patients are often used to make the initial diagnosis. Adenomyosis can lead to infertility and have adverse effect on the whole pregnancy process. Although adenomyosis is a benign disease, more and more reports in recent years have confirmed the risk of malignant transformation. Studies have shown that patients have endometrial cancer with adenomyosis, which protects against cancer invasion and infiltration, tend to have better clinical outcomes. Treatment of adenomyosis includes medication and surgery. Clinical studies have confirmed that there is no radical drugs, and surgery is the main treatment.

Key words: Adenomyosis;, Pregnancy;Endometrial neoplasms;, Diagnosis;, Therapy

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