Journal of International Obstetrics and Gynecology ›› 2022, Vol. 49 ›› Issue (6): 668-674.doi: 10.12280/gjfckx.20220546

• Obstetric Physiology & Obstetric Disease: Review • Previous Articles     Next Articles

Progress in Clinical Application of Antibiotics in Obstetrics

PAN Yu-xia, XIANG Qing-yi, BAI Xiao-xia()   

  1. Department of Obstetrics, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China
  • Received:2022-07-06 Published:2022-12-15 Online:2023-01-11
  • Contact: BAI Xiao-xia E-mail:baixiaoxia@zju.edu.cn

Abstract:

Pregnant women have unique anatomical and physiological characteristics during pregnancy, delivery and puerperium, and are prone to genital tract bacterial infection. The progression of the disease can lead to adverse pregnancy outcomes such as premature birth, abortion, premature rupture of membranes, intra amniotic infection, fetal distress, stillbirth, puerperal infection, sepsis and so on. At present, antibiotics, as the most effective drugs to prevent and treat bacterial infections, are widely used in obstetric clinic. It is worth noting that rational use of drug for pregnant women should not only take into account the illness itself, but also take into account the safety of mother and child during pregnancy and lactation. Therefore, there are still many problems in the actual clinical application of antibiotics in obstetrics, which should be paid more attention to. This article reviews how to use antibiotics rationally, combined with different periods and common diseases, which is helpful to provide more theoretical basis for medication guidance during pregnancy and lactation.

Key words: Anti-bacterial agents, Reproductive tract infections, Bacterial infections, Puerperal infection, Pregnant women