Abstract: Objective：To analyze retrospectively those cases of borderline ovarian tumors（BOTs） from Renji Hospital, School of Medicine, Shanghai Jiao Tong University in recent 10 years, including the prognosis of BOTs and factors affecting the prognosis. Methods： A total of 72 patients with BOTs were retrospectively analyzed, from March 2004 to October 2014, including clinical features, diagnosis, treatment and follow-up visit. Results：The mean age at diagnosis was （46.4±17.3） years, including 30（41.7%） patients aged ≤40 years, 22（30.6%） postmenopausal patients, and 47（65.3%） asymptomatic patients. The serum level of CA125 was increased in 29（50.9%） patients, and the level of CA199 in 18（31.6%） patients. The median sonographic dimension of serous BOTs mass （80 mm） was significantly larger than that of mucinous mass (185 mm) （P＜0.001）. 52（72.2%） patients were at stage Ⅰa, while 12（16.7%） at stage Ⅱ-Ⅳ. The recurrence was seen in 6 patients （6/72）, and the recurrence rate was only related to the surgical procedure by the COX regression analysis （P=0.045）. Conclusions：Patient with BOTs are younger, while the preoperative diagnosis rate is not high. The prognosis of BOTs treatment is relatively satisfying if the early diagnosis was achieved. The long-term follow-up visit is essential since BOTs have two reasonably high rates, recurence rate and canceration rate. Surgical procedure is the main factor related to recurrence. It is necessary to keep the long-term follow-up visit, including the survival period and affecting factors, in those BOTs patients after operation.

Key words: Ovarian neoplasms, Recurrence, Prognosis, Retrospective studies