Journal of International Obstetrics and Gynecology ›› 2018, Vol. 45 ›› Issue (1): 28-32.

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Research Progress of Risk Factors for Development of Type 2 Diabetes Mellitus in Women with a History of Gestational Diabetes Mellitus

YE Hua-ying,LI Hua-ping   

  1. Department of Obstetrics and Gynecology,Shanghai Jiao Tong University Affiliated Sixth People′s Hospital,Shanghai 200233,China(YE Hua-ying,LI Hua-ping);Medical College of Soochow University,Soochow 215006,Jiangsu Province,China(YE Hua-ying)
  • Received:2017-10-17 Revised:2018-01-05 Published:2018-02-15 Online:2018-02-15
  • Contact: LI Hua-ping,E-mail:lihp@sjtu.edu.cn E-mail:lihp@sjtu.edu.cn;15862536703@163.com

Abstract: Gestational diabetes mellitus(GDM) is a common obstetric complication and increases the risk of pregnancy. Due to changes in lifestyle and diet, the incidence of GDM is gradually increasing. Blood glucose testing of most women with GDM is normal after delivery, but long-term risk for type 2 diabetes mellitus (T2DM) is still there. Women with a history of GDM have become potential susceptible population of diabetes, metabolic syndrome in the future. Older age, obesity, family history of diabetes, levels of plasma glucose, the need of insulin during pregnancy, and earlier diagnosis of GDM is increasingly valued. By recognizing the related risk factors and prediction markers, which include clinical features in pregnancy and postpartum, biochemical indicators, molecular genetic markers et al, predict the risk  of GDM progressing to T2DM in the future and improve the public′s awareness of risk for GDM women postpartum follow-up. Early lifestyle intervention and drug treatment can prevent or delay the onset of T2DM after GDM, improve health outcomes of women with a history of GDM.

Key words: Diabetes, gestational;, Diabetes mellitus, type 2, Postnatal care, Risk factors, Forecasting

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