Abstract: Uterine leiomyoma is the most common benign tumor of female reproductive system. With the delay of childbearing age and the opening of China′s second child policy, many patients with uterine leiomyoma still have fertility requirements. However, the best treatment for such patients has not yet been determined. Although some suggestions have been given for the treatment of infertility with uterine fibroids in relevant consensus or guidelines at domestic and abroad, these suggestions are often ambiguous and sometimes contradictory. Some guidelines point out that hysteromyomectomy is not recommended for women with reproductive needs unless hysteromyoma has caused complications of pregnancy. Some guidelines consider that uterine fibroids combined with infertility is a treatment indication, while others suggest that the treatment of uterine fibroids with infertility should be based on the type of uterine fibroids. It is recommended to perform surgery on submucosal fibroids or intramural fibroids that cause changes in endometrium, and other areas of fibroids are not recommended to treat, regardless of the size of the fibroids. Based on the literature reports and relevant guidelines, this paper discusses the basic principles of treatment of infertility complicated with uterine leiomyoma, in order to provide reference for its standardized treatment.

Key words: Infertility, female, Uterus, Myoma, Gynecologic surgical procedures, Pregnancy