Abstract: Ovarian cancer is one of the common malignant tumors in gynecology. The most common pathological type is adenocarcinoma. Primary ovarian squamous cell carcinoma is a rare ovarian malignant tumor with a low incidence and high degree of malignancy. The etiology and tissue origin are not clear. There are no standardized clinical practice guidelines to guide its diagnosis and treatment. It is not sensitive to radiation therapy and the drug treatment effect on it is poor. Surgery is the main treatment way, but the prognosis is poor. This paper reports a case of primary ovarian squamous cell carcinoma admitted to the Gansu Provincial Hospital on December 31, 2018, and reviews the relevant literature.

Key words: Primary ovarian squamous cell carcinoma;, Ovarian neoplasms;, Neoplasms, squamous cell, Diagnosis, Diagnosis, differential