Journal of International Obstetrics and Gynecology ›› 2025, Vol. 52 ›› Issue (5): 508-511.doi: 10.12280/gjfckx.20250206

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

A Case of Malignant Mesothelioma of the Pelvic Peritoneum

ZHU Ran-ran, YU Chun-li()   

  1. Department of Gynecology, Tai'an Central Hospital, Tai'an 271000, Shandong Province, China
  • Received:2025-03-04 Published:2025-10-15 Online:2025-10-16
  • Contact: YU Chun-li E-mail:Chunliyu1970@163.com

Abstract:

A case of peritoneal malignant mesothelioma (PMM) is reported. The patient presented due to a palpable abdominal mass. Color Doppler ultrasound indicated a hypoechoic mass in the pelvic cavity. Before the operation, the patient was tentatively diagnosed with a pelvic malignant tumor. Subsequently, a laparoscopic exploration was performed, and the lesions on the surface of the bilateral fallopian tubes and ovaries were resected during the operation. The nature of the mass could not be determined by introperative pathological examination. After the operation, the routine pathological examination, following further consultation, confirmed it as a malignant tumor, suspected to be a malignant mesothelioma, possibly originating from the peritoneum. Then, a cytoreductive surgery was carried out. After the operation, the patient's symptoms were relieved, but the patient refused further treatment. PMM is a clinically rare, highly invasive malignant tumor originating from serosal mesothelial and sub-mesothelial cells. It commonly occurs in the pleura and peritoneum and is closely associated with asbestos exposure. The disease has an insidious onset, lacks typical symptoms, and has low imaging specificity, posing certain difficulties in clinical diagnosis and treatment. Most cases are diagnosed at an advanced stage, with a poor prognosis. The main treatment for PMM is cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy.

Key words: Pelvic neoplasms, Peritoneal neoplasms, Mesothelioma, malignant, Diagnosis, Therapy