Abstract: Objective：To study the association between environmental adverse factors exposure and embryo loss in early pregnancy， explore the probable risk factors for embryo growth and development and embryo abortion on life style and environmental aspect. Methods：Collect the new cases of embryo loss in four general hospitals of Tianjin from April 2009 to April 2010，select the women that have the request for abortion operation in normal pregnancy as control. A questionnaire was administered by trained interviewers for information about environmental adverse factors contact of wife and husband in and before pregnancy. Analysis probable environmental risk factors and confidential intervals of ORs for embryo loss in separate models， multiple linear regression and logistic regression model. Results：Cooking frequently during pregnancy， more daily traffic hours， decoration history in early pregnancy and toxic matter（pesticide， paint） contact of their husband during the three months before pregnancy may have adverse effects on embryo growth and development，while maternal education was a protective factor. Conclusions：Women exposed to traffic，cooking and decoration related environmental adverse factors will be potential threat to embryo normal development in early pregnancy.

Key words: Environmental pollution, Fetal growth retardation, Questionnaires, Smog, Air pollution, Air pollution