Journal of International Obstetrics and Gynecology ›› 2010, Vol. 37 ›› Issue (1): 50-52.

• 综述 • Previous Articles     Next Articles

Current Applications in Animal Optical Imaging Technologies with Bioluminescence and Fluorescence in the Experimental Models of Endometriosis

ZHENG Ting-ting;LIU Yi   

  1. Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022,China Corresponding author: LIU Yi, E-mail:liqun94@163.com
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-02-15 Online:2010-02-15
  • Contact: LIU Yi

Abstract: The experimental animal models as a xenographic host of induced endometriosis for relative
biological behavior study of endometriosis have been developed and are of high value for the evaluation of the etiopathogenisis, pathogenesis and therapeutics underlying the development of this disease. This review describes these animal models of induced endometriosis using fluorescence in vivo imaging and bioluminescence to quantify the ectopic lesions of both size and number and assesses their different potentials and limitations in regard to endometriosis research, with the aim of developing novel non-invasive diagnostic tools.

Key words: Optical imaging, Green fluorescent protein, CFSE, Luciferase, Endometriosis, Animal model