Abstract: With the morbidity of 5%~10% in premenopausal women，polycystic ovary syndrome （PCOS） is an exceptionally commen disorder . Its features are chronic anovulation or few ovulations，polycystic ovaries increase in size and hyperandrogenism. In addition，it is also characterized by insulin resistance （IR） and β-cell dysfunction. The conception rate of patients with PCOS is fallen，and patient’s prevalence rate of spontaneous abortion during pregnancy and gestational diabetes is higher than the normal persons.Besides，these patients are at higer risk of suffering from endometrial carcinoma .Some result from several recent studies，showed that patient’s incidence of metabolic syndrome （MS） was increased. Metabolic syndrome has a significant relationship with cardiovascular diseases and IR. At present，many scholars have made extensive researches on the impact of IR and PCOS，pointing out that it is effective to improve PCOS patients’endocrine condition and their reproduction by ameliorate their insulin resistance. Lifestyle adjustment can be a efficient measure to achieve this aim，besides，oral hypoglycemic agents can also be an effective method to treat the insulin resistance in PCOS.

Key words: Polycystic ovary syndrome, Insulin resistance, Metabolic syndrome X, Pregnancy complications, cardiovascular, Risk factors