Abstract: Tumor-related inflammation including lymphocyte infiltration into tumor tissue. Tumor-associated macrophages（TAM） are important regulator of cells，mainly involved in tumor-associated inflammatory. While M2-tumor associated macrophage is the main subtype macrophages which expression in the tumor microenvironment，promote and coordinate neoplastic growth. M2-type TAM inhibite the anti-tumor activity of T cells and promote angiogenesis by over expressing CCL-18，VEGF，and MMP-9. M2-type TAM infiltration in tumor tissue might be an important indicator of tumor development，metastasis and prognosis，and providing a new approach to treatment of ovarian cancer. Polarization-type tumor-associated macrophages play an important role in the development of ovarian cancer and provide a new direction in early diagnosis and treatment of ovarian cancer .

Key words: Ovarian neoplasms, Macrophages, Tumor escape, M2-tumor associated macrophage