国际妇产科学杂志

国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (4): 327-330.

• 综述 • 上一篇    下一篇

人类子宫内膜肿瘤干细胞的研究进展

张继雯,宋殿荣   

  1. 300150 天津中医药大学第二附属医院妇科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-08-15 发布日期:2013-08-15
  • 通讯作者: 宋殿荣

Research Progress on Human Endometrial Tumor Stem Cells

ZHANG Ji-wen， SONG Dian-rong   

  1. Department of Gynecology，the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine，Tianjin 300150，China.
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-08-15 Online:2013-08-15
  • Contact: SONG Dian-rong

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5085

被引次数

1

摘要： 子宫内膜癌是妇科常见的三大恶性肿瘤之一，严重威胁女性的生活和健康。子宫内膜肿瘤干细胞与子宫内膜肿瘤的发生、发展、转移和复发密切相关，因而可能是导致子宫内膜肿瘤治疗失败的主要原因。目前已成功分离和鉴定出子宫内膜干细胞。子宫内膜肿瘤干细胞可能来源于正常子宫内膜干细胞或其分化的细胞，对子宫内膜肿瘤干细胞的表面标记物及其分离和鉴定方法的探索已取得一定成果。综述子宫内膜肿瘤干细胞的研究进展。

关键词: 干细胞, 子宫内膜, 肿瘤干细胞, 生物学标记

Abstract: Endometrial tumor is one of the most common gynecological malignancies afflicting the lives and health of the women. Endometrial tumor stem cells， which may be the main reason why anti-endometrial tumor therapy fails， are possibly responsible for the development， progression， metastasis and recurrence of the endometrial tumor disease. At present endometrial stem cells have been successfully separated and identified. Endometrial tumor stem cells may originate from normal endometrium stem cells or its differentiated cells， exploration of whose surface markers， separation and identification methods has obtained some achievements. This article overviewed the progress in experiments of endometrial tumor stem cells.

Key words: Stem cells, Endometrium, Neoplastic stem cells, Biological markers