国际妇产科学杂志

国际妇产科学杂志 ›› 2017, Vol. 44 ›› Issue (1): 27-30.

• 综述 • 上一篇    下一篇

抗N-甲基-D-天门冬氨酸受体脑炎合并卵巢畸胎瘤的研究进展

曾靖   

  1. 中国医学科学院北京协和医学院北京协和医院妇产科
  • 收稿日期:2016-07-15 修回日期:2016-11-21 出版日期:2017-02-15 发布日期:2017-03-28
  • 通讯作者: 曾靖 E-mail:331222004@qq.com

Research advances in ovarian teratoma associated with anti-N-methyl-D-aspartate receptor encephalitis

Jing ZENG   

  • Received:2016-07-15 Revised:2016-11-21 Published:2017-02-15 Online:2017-03-28
  • Contact: Jing ZENG E-mail:331222004@qq.com

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摘要： 摘要：抗N-甲基-D-天门冬氨酸受体脑炎是近年新发现的一种自身免疫性脑炎，多合并畸胎瘤等生殖细胞肿瘤，发病机制可能为抗N-甲基-D-天门冬氨酸受体抗体干扰神经信号传递所致，临床表现呈多样性，治疗以免疫治疗合并肿瘤切除为主，预后较好。本文主要对于抗N-甲基-D-天门冬氨酸受体脑炎合并卵巢畸胎瘤的相关研究进行综述，以期提高临床医生对该新发现疾病的认识。

关键词: 关键词：抗N-甲基-D-天门冬氨酸受体脑炎, 卵巢畸胎瘤, 诊断, 治疗

Abstract: Abstract: Anti-N-methyl-D-aspartate receptor encephalitis, which is always associated with germ cell tumors such as teratoma, is an autoimmune encephalitis discovered recently. The pathogenesis is high likely related to anti-N-methyl-D-aspartate antibody, which have obstruct the transmission of neural signals. Its clinical manifestation is diverse and the treatment combines immunotherapy with tumor resection. The prognosis is also good. This review mainly introduce the researches on anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma to improve the awareness of clinician on this recent discovered disease.

Key words: Key words: Anti-N-methyl-D-aspartate receptor encephalitis, Ovarian teratoma, Diagnosis, Therapy