国际妇产科学杂志 ›› 2018, Vol. 45 ›› Issue (6): 686-690.

• 综述 • 上一篇    下一篇

子宫内膜异位症对妊娠结局影响的研究进展

张秀香,阿扎提古丽·阿布拉,高桂芹△,米日古丽·牙生   

  1. 848000  新疆维吾尔自治区和田地区人民医院西院区(张秀香,阿扎提古丽·阿布拉,米日古丽·牙生);天津市中心妇产科医院(高桂芹)
  • 收稿日期:2018-07-11 修回日期:2018-08-23 出版日期:2018-12-15 发布日期:2018-12-15
  • 通讯作者: 高桂芹,E-mail:ggqzxfc@163.com E-mail:ggqzxfc@163.com

The Research Progress on the Effect of Endometriosis on Pregnancy Outcomes

ZHANG Xiu-xiang,A zha ti gu li·a bu la,GAO Gui-qin,Mi ri gu li·ya sheng   

  1. Hetian the People′s Hospital West Campus,Hetian 848000,Xinjiang Uygur Autonomous Region,China (ZHANG Xiu-xiang, A zha ti gu li·a bu la, Mi ri gu li·ya sheng);Tianjin Central Hospital of Gynecology Obstetrics, Tianjin 300100, China(GAO Gui-qin)
  • Received:2018-07-11 Revised:2018-08-23 Published:2018-12-15 Online:2018-12-15
  • Contact: GAO Gui-qin,E-mail:ggqzxfc@163.com E-mail:ggqzxfc@163.com

摘要: 子宫内膜异位症(EMs)是一种妇科常见疾病,常发生于育龄期妇女,以盆腔疼痛和不孕为主要表现,严重困扰育龄期妇女的身心健康。近年研究发现EMs不仅可以引起不孕,还可以导致不良的妊娠结局。研究显示EMs患者在妊娠早期发生流产、异位妊娠的风险增加,在妊娠中晚期发生早产、前置胎盘、妊娠期高血压疾病-子痫前期以及小于胎龄儿的风险增加,剖宫产分娩率增加。EMs与上述不良妊娠结局有关,其导致不孕以及不良妊娠结局的机制复杂,涉及EMs发生、发展过程中的病理生理改变,阐明其发生机制对EMs患者不良妊娠结局的防治具有重要意义。

关键词: 子宫内膜异位症, 妊娠结局, 流产, 自然, 早产, 前置胎盘

Abstract: Endometriosis(EMs) is a common gynecological disease, which often occurs in women of reproductive age. Pelvic pain and infertility are the main manifestations, which seriously disturb the physical and mental health of reproductive women. Recent studies have found that EMs can not only cause infertility, but also lead to adverse pregnancy outcomes. Studies have shown that women with EMs had a statistically significantly higher risk of miscarriage, ectopic pregnancy in the early pregnancy outcomes, and preterm birth, placenta previa, gestational hypertension and preeclampsia, small for gestational age, and cesarean delivery in the middle-late pregnancy outcomes compared with the healthy controls. EMs is associated with these above adverse pregnancy outcomes. The mechanism of EMs leading to infertility and adverse pregnancy outcomes is complex. It involves the pathophysiological changes of EMs during its occurrence and development. It is important to elucidate the mechanism of EMs for the prevention and treatment of adverse pregnancy outcomes in EMs patients.

Key words: Endometriosis, Pregnancy outcome, Abortion, spontaneous, Premature birth, Placenta previa