关键词: 宫颈肿瘤, 手术后并发症, 尿失禁, 危险因素, Logistic模型

Abstract: Objective: To investigate the risk factors of postoperative urinary incontinence (UI) in patients with cervical cancer (CC) and provide evidence for prevention and individualized treatment of UI after radical resection of CC. Methods: This is a retrospective analysis of patients who had UI or no postoperative complications after radical resection of CC at Peking University People′s Hospital from January 2013 to December 2018. 14 patients with urinary incontinence in stage ⅠA1 to ⅡA2 after surgery were assigned to UI group and another 43 patients who were treated with radical CC resection at the same time without UI were selected as the control group. The general data and clinicopathological data were recorded and the risk factors of CC complicated with UI were analyzed. Results: Univariate analysis showed UI was closely related with difference in hemoglobin levels before and after surgery, number of resected lymph nodes, operative time, length of vaginal amputation and difference between annual surgery frequencies of surgeons (P＜0.05). Multivariate Logistic analysis revealed that the high hemoglobin difference levels before and after surgery (OR=1.164, 95%CI: 1.006-1.348, P=0.042), longer operative time (OR=79.896, 95%CI: 2.033-3 139.492, P=0.019) and low annual surgery frequencies of the surgeon (OR=13.116, 95%CI: 1.046-164.436, P=0.046) were significantly associated with postoperative UI. Conclusions: For CC patients with high hemoglobin difference levels before and after surgery, longer operative time and low annual surgery frequencies of the surgeon, effective comprehensive measures should be taken in time to prevent UI.

Key words: Uterine cervical neoplasms, Postoperative complications, Urinary incontinence, Risk factors, Logistic models