国际妇产科学杂志 ›› 2020, Vol. 47 ›› Issue (3): 258-261.

• 综述 • 上一篇    下一篇

人乳头瘤病毒与妊娠结局的相关性

王宝娟,宫政,胡祖贤,夏天   

  1. 300381  天津中医药大学第一附属医院生殖中心
  • 收稿日期:2019-12-04 修回日期:2020-01-10 出版日期:2020-06-15 发布日期:2020-06-23
  • 通讯作者: 夏天,E-mail:xiatian76@163.com E-mail:xiatian76@163.com
  • 作者简介:2020-03-01
  • 基金资助:
    国家自然科学基金(81774351)

Human Papillomavirus and Pregnancy Related Problems

WANG Bao-juan, GONG Zheng, HU Zu-xian, XIA Tian   

  1. Reproductive Center, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
  • Received:2019-12-04 Revised:2020-01-10 Published:2020-06-15 Online:2020-06-23
  • Contact: XIA Tian, E-mail:xiatian76@163.com E-mail:xiatian76@163.com

摘要: 人乳头瘤病毒(human papilloma virus,HPV)是生殖道感染最常见的病毒之一,HPV尤其是高危型HPV的反复感染易转变为宫颈上皮内瘤变,甚至会诱发宫颈、肛门及口咽腔的恶性肿瘤。育龄期男性与女性是HPV感染的多发群体,有文献报道,HPV感染可能对生殖健康与妊娠产生不利影响。结合近年发表的国内外文献对HPV感染与妊娠结局相关问题,从HPV妊娠期易感性、HPV感染对异常妊娠的影响、HPV感染与分娩方式及新生儿结局、HPV感染对辅助生殖技术妊娠成功率及妊娠结局的影响、接种HPV疫苗对妊娠的影响几方面进行综述。

关键词: 乳头状瘤病毒感染;, 妊娠结局;, 生殖技术, 辅助;, 生殖细胞;, 流产, 自然;, 妊娠, 异位

Abstract: Human papilloma virus(HPV) is one of the most common viruses in reproductive tract infections. The recurrent infection of HPV virus, especially high-risk type HPV, can be turned into cervical epithelial endothelial tumor, and may even induce malignant tumors in the cervix, anus and mouth cavity. Men and women of childbearing age are the most common group of HPV infections, and it has been reported that HPV infection may have adverse effects on reproductive health and pregnancy. In the light of the domestic and international literature published in recent years, the issues related to HPV infection and pregnancy outcome are reviewed. This paper expounds the susceptibility of HPV infection during pregnancy, the effect of HPV infection on abnormal pregnancy, the way of HPV infection and delivery and neonatal outcome, the effect of HPV on success rate of assisted reproductive technology and pregnancy outcome, and the effect of HPV vaccine on pregnancy.

Key words: Papillomavirus infections;, Pregnancy outcome;, Reproductive technology, assisted;, Germ cells;, Abortion, spontaneous;, Pregnancy, ectopic