妊娠期高血压疾病与死胎关系的研究进展

doi:10.12280/gjfckx.20250195

摘要/Abstract

摘要：

死胎是严重的妊娠并发症之一，死胎的发生不仅会给孕产妇及其家庭带来巨大的心理负担和伤害，同时也给社会带来较大的经济负担。妊娠期高血压疾病（hypertensive disorders of pregnancy，HDP）是妊娠期常见的并发症之一。近年研究表明，HDP是导致死胎的重要母体因素之一，而关于不同高血压分级对HDP和死胎的影响仍知之甚少，血压控制水平与死胎的关系仍存在争议，且HDP孕妇应用阿司匹林等药物治疗对HDP是否有益也尚存争议。综述HDP对死胎的影响、药物治疗HDP对死胎的影响、HDP导致死胎的作用机制及HDP导致死胎的管理，以期为死胎的预防管理提供更科学、准确的指导。

关键词: 妊娠, 高血压, 高血压, 妊娠性, 死胎, 治疗, 孕期管理

Abstract:

Stillbirth is one of the severe complications of pregnancy. The occurrence of stillbirth not only brings huge psychological burdens and harm to pregnant women and their families but also imposes relatively large economic burden on society. Hypertensive disorders of pregnancy (HDP) are one of the common complications during pregnancy. Recent studies have shown that HDP is one of the important maternal factors leading to stillbirth. However, little is known about the influence of different hypertension classifications on HDP and stillbirth. The relationship between blood pressure control levels and stillbirth remains controversial, and there are also disputes about whether the use of drugs such as aspirin in the treatment of HDP in pregnant women is beneficial. This review summarizes the influence of HDP on stillbirth, the impact of drug treatment for HDP on stillbirth, the mechanism by which HDP leads to stillbirth, and the management of stillbirth caused by HDP, aiming to provide more scientific and accurate guidance for the prevention and management of stillbirth.

Key words: Pregnancy, Hypertension, Hypertension, pregnancy-induced, Fetal death, Therapy, Pregnancy management

姚政洋, 伍绍文, 刘瑞霞, 阴赪宏. 妊娠期高血压疾病与死胎关系的研究进展[J]. 国际妇产科学杂志, 2025, 52(4): 377-383.

YAO Zheng-yang, WU Shao-wen, LIU Rui-xia, YIN Cheng-hong. Research Progress on the Relationship between Hypertensive Disorders of Pregnancy and Stillbirth[J]. Journal of International Obstetrics and Gynecology, 2025, 52(4): 377-383.

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