Protein Tyrosine Phosphatase 1B and Insulin Signal Transduction in Gestational Diabetes Mellitus

Journal of International Obstetrics and Gynecology ›› 2010, Vol. 37 ›› Issue (2): 90-92.

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Protein Tyrosine Phosphatase 1B and Insulin Signal Transduction in Gestational Diabetes Mellitus

GAO Xiao-li, NIU Xiu-min

Department of Obstetrics and Gynecology, Tianjin Medical University General Hospital, Tianjin 300052, China

Received:2009-04-13 Revised:1900-01-01 Published:2010-04-15 Online:2010-04-15

Abstract

Abstract: Protein tyrosine phosphatase 1B （PTP 1B） has close relationship with insulin resisitance by
inhibiting the insulin signal transduction pathway. Insulin resistance is the main cause of pathogenetic in Gestational diabetes mellitus, and the insulin signal transduction pathway may be the important cellular mechanisms of GDM.
Investigating the relationship between PTP 1B and GDM insulin signal transduction, further, to research mechanisms of insulin resistance in GDM, for preventing and interfering GDM, reducing the complications of maternity and fetus

Key words: Protein tyrosine phosphatase 1B, Gestational diabetes mellitus, Insulin resistance, Insulin signal transduction

GAO Xiao-li;NIU Xiu-min. Protein Tyrosine Phosphatase 1B and Insulin Signal Transduction in Gestational Diabetes Mellitus[J]. Journal of International Obstetrics and Gynecology, 2010, 37(2): 90-92.

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Protein Tyrosine Phosphatase 1B and Insulin Signal Transduction in Gestational Diabetes Mellitus

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