Abstract: As Lymph node metastasis is one of the earliest features of tumor cell spread in cervical cancer, assessment of the regional lymph nodes impacts the determining prognosis and planning adjuvant therapy directly. The sentinel lymph node（SLN） study, which could reflect the status of the entire pelvic lymphatic nodes, without removing all lymph nodes would spare most of patients with the loss of unaffected lymph nodes in early stage cervical cancer and give the chance of radical hysterectomy without pelvic lymphadenectomy. There are three techniques for sentinel lymph node identification; using blue dye alone, using 99Tcm colloid alone, or the combined method. Detecting micrometastases in lymph node with the use of immunohistochemistry IHC, the analysis of SCC-Ag levels or the determination of HPV status, may help to detect metastases of SLN.

Key words: Uterine cervical neoplasms, Lymph nodes, Sentinel lymph node biopsy, Neoplasm metastasis